Specialties: Over the past decades, he has been engaged in treatment for cardiovascular critical disease, and has made in-depth research on the pathogenesis of aortic dissection, the therapeutic effect of vascular stem cells, and treatment for brain injury after cardiac arrest.

Clinical Interests: Cardiovascular critical disease; treatment for brain injury after cardiac arrest

Education:

1991.09-1996.07 Jining Medical Univercity Clinical Medicine B.A.

2000.09-2003.07 Sun Yat-sen University Emergency Medicine M.A.

2005.09-2008.07 Sun Yat-sen University Emergency Medicine M.D.

Awards and Honors:

[1]Young and middle-aged experts with outstanding contributions to national health in 2017

[2]Medical Leading Talents/ Outstanding Young Medical Talents of Guangdong Province in 2018

[3]Third-class Merit for “fighting SARS” by Guangdong provincial Party committee and provincial government in 2003

Professional memberships:

[1]Standing Committee Member of Guangdong Medicial Association Emergency Branch

[2]Vice chairman of Southern Medical Rescue Training Center, Health Emergency Committee, Chinese Research Hospital Association

[3]Vice chairman of Guangdong Provicial CPR Training Committee, CPR Committee of China Research Hospital Association

[4] Member of emergency branch of Chinese Medical Association

[5] Vice chairman of quality control group of emergency branch of Chinese Medical Association

[6] Chairman of Tibet Aid Committee of Guangdong Medical Association

Publications:

（1）Yang KH#, Ren J#, Li X#, Wang Z, Cui SM, Sang WT, Xu TH, Zhang J, Yu JQ, Liu ZP, Shang HX, Pang JJ, Huang XR, Chen YG*, Xu F*. Prevention of aortic dissection and aneurysm via an ALDH2-mediated switch in vascular smooth muscle cell phenotype. European Heart Journal. 2020 ;41(26):2442-2453. DOI:: 10.1093/eurheartj/ehaa352.(共同第一作者，SCI收录，IF:22.673)

（2）Hong YM, He HW, Jiang GJ, Zhang H, Tao WY, Ding Y, Yuan DS, Liu J, Fan HM, Lin F, Liang XT*, Li X*, Zhang YL*. MiR-155-5p Inhibition Rejuvenates Aged Mesenchymal Stem Cells and Enhances Cardioprotection following Infarction. Aging Cell, 2020. e13128. DOI: 10.1111/acel.13128. (共同通讯作者，SCI 收录，IF:7.346）

（3）Zhou XK, Hong YM, Zhang H, Li X*. Mesenchymal Stem Cell Senescence and Rejuvenation: Current Status and Challenges. Frontiers in Cell and Developmental Biology. 2020; 8:364. DOI: 10.3389/fcell.2020.00364. eCollection 2020. (通讯作者，SCI收录，IF: 5.201)

（4）You W, Hong YM, He HW, Huang XR, Tao WY, Liang XT, Zhang YL*, Li X*. TGF-β Mediates Aortic Smooth Muscle Cell Senescence in Marfan Syndrome. Aging-US, 2019;11(11):3574-3584. (通讯作者，SCI 收录，IF:5.515）

（5）Zhang YL#, Zhu WW#, He HW#, Fan BH, Deng R, Hong YM, Liang XT, Zhao HY, Li X*, Zhang FX*. Macrophage Migration Inhibitory Factor Rejuvenates Aged Human Mesenchymal Stem Cells and Improves Myocardial Repair. Aging-US, 2019, 11(24): 12641-12660. (共同通讯作者，SCI 收录，IF:5.515）

（6）Li X#, Hong YM#, He HW, Jiang GJ, You W, Liang XT, Fu QL, Han S, Lian QZ, Zhang YL*. FGF21 Mediates Mesenchymal Stem Cell Senescence via Regulation of Mitochondrial Dynamics. Oxidative Medicine and Cellular Longevity. 2019;2019:4915149. (第一作者，SCI 收录，IF:4.868）

（7） Huang XR, Zhang H, Liang XT, Hong YM, Mao MM, Han Q, He HW, Tao WY, Jiang GJ, Zhang YL*, Li X*. Adipose-Derived Mesenchymal Stem Cells Isolated from Patients with Abdominal Aortic Aneurysm Exhibit Senescence Phenomena. Oxidative Medicine and Cellular Longevity. 2019, 2019: 1305049. (通讯作者，SCI 收录，IF:4.868）

（8）He HW, Yu BQ, Liu ZP, Ye G, You W, Hong YM, Lian QZ, Zhang YL*, Li X*. Vascular Progenitor Cell Senescence in Patients with Marfan Syndrome. Journal of Cellular and Molecular Medicine. 2019; 23(6):4139-4152. (通讯作者，SCI 收录，IF:4.658）

（9） Liu XL#, Li X#, Zhu WW#, Zhang YL, Hong YM, Liang XT, Fan BH, Zhao HY, He HW, Zhang FX*. Exosomes from mesenchymal stem cells overexpressing MIF enhance myocardial repair. Journal of cellular physiology 2020. DOI: 10.1002/jcp.29456. (共同第一作者,SCI 收录，IF:4.522)