Specialties: Oral and Maxillofacial Surgery :
Clinical Interests：
1.Oral and maxillofacial malignant tumors (including tongue cancer, buccal cancer, gingival cancer and other malignant tumors) surgery and comprehensive treatment
2.Benign and malignant tumors of jaws (including odontogenic and non-odontogenic tumors, such as odontogenic cyst and ameloblastoma, etc.)
3.Maxillofacial bone deformities (orthognathic surgery)
4.Salivary disease ( parotid, submandibular and sublingual gland tumors, etc.)
5.Infection disease of maxillofacial area,radiation-induced or medication-related jaw bone osteonecrosis. congenital cleft lip and palate, intractable jaw bone fracture
6.Temporomandibular joint disease, trigeminal neuralgia and other diseases
7.Especially good at the radical resection of oral cancer, neck lymph node dissection and flap repair and reconstruction
Bio：
Senior Doctor, Department of Oral & Maxillofacial Surgery, Guangdong Academy of Medical Sciences & Guangdong Provincial People’s Hospital. (Feb.2021- present)
Associate Senior Doctor, Department of Oral & Maxillofacial Surgery, Guangdong Academy of Medical Sciences & Guangdong Provincial People’s Hospital. (Jan.2010- Jan.2021)
Doctor in Charge, Department of Oral & Maxillofacial Surgery, Guangdong Academy of Medical Sciences & Guangdong Provincial People’s Hospital. (Jan.2005- Dec.2009)
Residency, Department of Oral & Maxillofacial Surgery, Guangdong Academy of Medical Sciences & Guangdong Provincial People’s Hospital.(Jul.2002- Dec.2004)
Residency, Major in Oral and Maxillofacial Surgery, Bengbu, Anhui, China (Jul.1994-Jul.1999)
Education：
Postdoctoral and clinical fellow, MD Anderson Cancer Center, Houston, USA(2015-2016)
Ph.D. Oral and Maxillofacial Surgery, Sun Yat-sen University, China (2007-2011)
M.D. Oral and Maxillofacial Surgery, Sun Yat-sen University, China (1999-2002)
Bachelor's degree. Stomotalogy, Anhui Medical University, China (1989-1994)
Awards and Honors (Grants)：
1.Science and Technology Planning Project of Guangzhou. (Grant No: 201904010008)
2.Medical Research Foundation of Guangdong Province. (Grant No:B2018030)
3.Science and Technology Program of Guangdong Province (Grant No: 2013B021800159)
4.Science and Technology Program of Guangdong Province (Grant No:2011B031800166)
5. Science and Technology Program of Guangdong Province (Grant No:2008B030301182）
6. Science and Technology Program of Guangdong Province (Grant No:2007B031514005）
Professional membership：
Member of the international committee of oral and maxillofacial surgery
Vice chairman of oral and maxillofacial surgery committee of Guangdong Stomatological Association
Vice chairman of maxillofacial-head and neck surgery committee of Guangdong Medical Association
Vice chairman of Oral health branch of Guangdong Health Care Association
Standing committee member of minimally invasive tumor committee of China Anticancer Association
Publications：
1. Zhu L#, Sturgis EM, Zhang H#, Lu Z#, Tao Y, Wei Q, Li G*. Genetic variants in microRNA-binding sites of DNA repair genes as predictors of recurrence in patients with squamous cell carcinoma of the oropharynx. Int J Cancer. 2017 Oct 1;141(7):1355-1364.
2. Zhu LJ#, Sturgis EM, Lu Z#, Zhang H#, Wei P, Wei Q, Li G*..Association between miRNA-binding site polymorphisms in double-strand break repair genes and risk of recurrence in patients with squamous cell carcinomas of the non-oropharynx. Carcinogenesis. 2017 Apr 1;38(4):432-438.
3. Li Y#, Sturgis EM, Zhu LJ, Cao X, Wei Q, Zhang H*, Li G*.E2F transcription factor 2 variants as predictive biomarkers for recurrence risk in patients with squamous cell carcinoma of the oropharynx. Mol Carcinog. 2017 Apr;56(4):1335-1343.
4. Shuqin Wang#, Yuncheng Li#, Guojun Li, Lijun Zhu#*. Mammary analogue secretory carcinoma presenting as a salivary gland neoplasm: a first clinical case report of an exceptionally rare tumor in China. Int J Clin Exp Med 2016;9(11):22632-22637.
5. Zhu LJ#, Yan WX, Chen ZW, Chen Y, Chen D, Zhang TH, Liao GQ*. Disruption of mediator complex subunit 19 (Med19) inhibits cell growth and migration in tongue cancer. World J Surg Oncol. 2013 May 27;11: 116.
6. Yang Wang#, Peng X#， Zhu LJ#，Hu L, Song Y*. Genetic variants of CHRNA5-A3 and CHRNB3-A6 predict survival of patients with advanced non-small cell lung cancer. Oncotarget. 2016，7（18）：26436-43.
7. Yuan Y#, Sturgis EM, Zhu L, Lu M, Li Y, Wei Q, Li G*. A functional variant at the miRNA binding site in E2F1 gene is associated with risk and tumor HPV16 status of oropharynx squamous cell carcinoma. Mol Carcinog. 2017 Mar;56(3):1100-1106.
8. Lu Z#*, Sturgis EM, Zhu L, Zhang H, Tao Y, Wei P, Wei Q*, Li G*. Mouse double minute 4 variants modify susceptibility to risk of recurrence in patients with squamous cell carcinoma of the oropharynx. Mol Carcinog. 2018 Mar;57(3):361-369.
9. Wenbin Yu#, Lijun Zhu#, Yuncheng Li*，Guojun Li*. Cytokine variants predict outcome of squamous cell carcinoma of the oropharynx. Int J Clin Exp Med. 2016,9(8):16682-16688.
10. Wenbin Yu#*, Lijun Zhu#, Guohui Xu,Yuntao Song,Guojun Li. Potential role of carbon nanoparticles in protection of parathyroid glands in patients with papillary thyroid cancer. Medicine (Baltimore). 2016,95(42):e5002.
11. Zhang TH#，Liu HC，Zhu LJ，Chu M，Liang YJ，Liang LZ，Liao GQ* .Activation of Notch signaling in human tongue carcinoma. Journal of Oral Pathology&medicine, 2010，40( 1),37-45.
12. Zhu LJ#*, Chen ZW, Hou QY, et al. Clinical value of PET in identifying cervical nodal metastases of tongue cancer:a comparison with CT/MRI and clinical palpation in 38 cases. Journal of Southern Medical University. 2009 Nov;29(11):2228-30.
13. Chen ZW#*, Zhu LJ, Hou QY, et al. Clinical application of positron-emission tomography for the identification of cervical nodal metastases of head and neck cancer compared with CT or MRI and clinical palpation. Chinese Journal of Stomatology. 2008 Dec; 43 (12): 705-8.
14. Chen D, Yan W, Liu Z, Zhang Z, Zhu L, Liu W, Ding X, Wang A, Chen Y. Downregulation of miR-221 enhances the sensitivity of human oral squamous cellcarcinoma cells to Adriamycin through upregulation of TIMP3 expression.Biomed Pharmacother. 2016 Feb;77:72-8.
15. Zhang H#, Sturgis E, Zhu L, Lu Z#, Tao Y, Zheng H*, Li G*. The Modifying Effect of a Functional Variant at the miRNA Binding Site in E2F1 Gene on Recurrence of Oropharyngeal Cancer Patients with Definitive Radiotherapy.Transl Oncol. 2018 Mar 22;11(3):633-638.
16.Zhu Lijun *, Wang Shuqin, Li Jun, et al., Treatment of chylous leakage after cervical lymph node dissection with Shapeilin: A clinical observation of 10 cases. Journal of Oral and Maxillofacial Surgery. 2020;30(4):256-259
17.Zhu Lijun *, Li Jun, Wang Shuqin et al. Comparison of the effect of heparin bridging and maintaining anticoagulation in anticoagulant patients with tooth extraction. Stomatological Research. 2020;36 (6) :554-556.
