个人简介

2002.09--2007.06 新乡医学院临床医学专业本科

2007.09--2010.06 广州医学院内科学专业硕士研究生

2010.07--2013.11 东莞市第三人民医院急诊科医生

2015.09--2018.06 南方医科大学急诊医学专业博士研究生

2018.09--2020.08 广东省心血管病研究所博士后

2020.09至今 广东省人民医院急诊科医生

研究方向

常见重症疾病的发病机制研究

代表性论著

1. Hongguang Ding; Mengting Liu; Yin Wen; Shiying Zhang; Hongke Zeng; Annals Graphic Medicine-COVID-19 and My Self-made Electronic Stethoscope. Annals of Internal Medicine, 2021; 174(8):W91-W93.

2. Hongguang Ding; Ya Li; Shenglong Chen; Yin Wen; Shiying Zhang; Ensi Luo; Xusheng Li; Wenhong Zhong; Hongke Zeng; Fisetin ameliorates cognitive impairment by activating mitophagy and suppressing neuroinflammation in rats with sepsis-associated encephalopathy. CNS Neuroscience & Therapeutics, 2022, 28(2):247-258.

3. Hongguang Ding; Yiyu Deng; Renqiang Yang; Qiaosheng Wang; Wenqiang Jiang; Yongli Han; Linqiang Huang; Miaoyun Wen; Wenhong Zhong; Xusheng Li; Fan Yang; Hongke Zeng; Hypercapnia induces IL-1β overproduction via activation of NLRP3 inflammasome: implication in cognitive impairment in hypoxemic adult rats. Journal of Neuroinflammation, 2018, 15(1): 4.

4. Hongguang Ding; Ya Li; Miaoyun Wen; Xinqiang Liu; Yongli Han; Hongke Zeng; Elevated intracranial pressure induces IL-1β and IL-18 overproduction via activation of the NLRP3 inflammasome in microglia of ischemic adult rats. International Journal of Molecular Medicine, 2021, 47(1): 183-194.

5. Hongguang Ding; Ya Li; Xusheng Li; Xinqiang Liu; Kangrong Wang; Miaoyun Wen; Wenqiang Jiang; Hongke Zeng; Hypercapnia promotes microglial pyroptosis via inhibiting mitophagy in hypoxemic adult rats. CNS Neuroscience & Therapeutics, 2020, 26(11): 1134-1146.

6. Hongguang Ding; Xinqiang Liu; Xusheng Li; Miaoyun Wen; Ya Li; Yongli Han; Linqiang Huang; Mengting Liu; Hongke Zeng; Hypercapnia exacerbates the disruption of the blood‑brain barrier by inducing interleukin‑1β overproduction in the blood of hypoxemic adult rats. International Journal of Molecular Medicine, 2020, 46(2): 762-772.

7. Hongguang Ding; Ya Li; Xusheng Li; Xinqiang Liu; Shenglong Chen; Mengting Liu; Hongke Zeng; Treatment with 7% and 10% CO2 enhanced expression of IL-1β, TNF-α, and IL-6 in hypoxic cultures of human whole blood. Journal of International Medical Research, 2020, 48(4): 1-12.

代表性课题

1. 国家自然科学基金青年项目，82002074，漆黄素通过抑制小胶质细胞焦亡缓解缺血性脑卒中后神经功能损害的机制研究，2021-01至2023-12，24万元，结题，主持

2. 广东省自然科学基金面上项目，2023A1515010267，FSP1抑制NCOA4介导的铁自噬缓解脑缺血-再灌注损伤的机制研究，2023-01 至 2025-12，10万元，在研，主持

3. 广州市科技计划项目，202002030338，漆黄素通过激活脑血管内皮细胞线粒体自噬减轻脓毒症诱导的认知功能损害的机制研究，2020-04至2023-03，20万元，结题，主持

学术任职

1. 中华医学会急诊医学分会中西医结合急救学组 委员

2. 中国病理生理学会炎症发热感染低温专业委员会 委员

3. 广东省基层医药学会高血压脑出血专委会 委员

4. 广东省医学教育协会肥胖代谢病管理专业委员会 副主任委员

执教课程（课程及教材建设）

1. 意识障碍与抽搐

荣誉奖励

无