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个人简介
2000.09--2005.06 中山大学中山医学院临床医学本科
2005.09--2010.06 中山大学中山医学院药理学博士
2010.07--2014.12 广东省人民医院心血管病学实习研究员
2014.12--2021.12 广东省人民医院心血管病学助理研究员
2021.12至今 广东省人民医院心血管病学副研究员
2014.03--2015.03 美国纽约州立大学奥尔巴尼分校公共卫生学院访问学者
2017.06--2017.08 日本北海道大学循环内科访问学者
2025.08至今 美国哈佛大学公共卫生学院博士后
研究方向
心血管病学，环境健康
代表性论著
1. Zhiqiang Nie#, Hongbin Xu#, Min Qiu#, Mingqin Liu, Chu Chu, Michael S. Bloom*, Yanqiu Ou*. Associations of maternal exposure to multiple plasma trace elements with the prevalence of fetal congenital heart defects: A nested case-control study. Science of the Total Environment, 2024, 912: 169409.（大通讯作者，IF=9.8）
2. Min Qiu, Jing Chen, Mingqin Liu, Zhiqiang Nie, Miaola Ke, Guanghui Dong, Haishan Zhao, Chengbin Zhou, Haiyan Zeng, Biaochuan He, Jimei Chen, Jian Zhuang*, Xiaohong Li*, Yanqiu Ou*. Single-cell RNA sequencing reveals the role of mitochondrial dysfunction in the cardiogenic toxicity of perfluorooctane sulfonate in human embryonic stem cells. Ecotoxicology and Environmental Safety, 2024, 270: 115945.（大通讯作者，IF=6.2）
3. Yougen Yuan, Xiangming Hu, Shanghong Zhang, Weimian Wang, Bingyan Yu, Yingling Zhou, Yanqiu Ou*, Haojian Dong*. Remnant cholesterol, preinflammatory state and chronic kidney disease: Association and mediation analyses. Renal Failure, 2024, 46(2): 2361094.（共同通讯作者，IF=3.0）
4. Bingyan Yu, Shize Jia, Tiantian Sun, Jieliang Liu, Junguo Jin, Shanghong Zhang, Qiyao Xiao, Haojian Dong*, Yanqiu Ou*. Sarcopenic obesity is associated with cardiometabolic multimorbidity in Chinese middle-aged and older adults: A cross-sectional and longitudinal study. The Journal of Nutrition, Health & Aging, 2024, 28(10): 100353.（大通讯作者，IF=4.3）
5. Mingqin Liu, Mohammed Zeeshan, Tiantian Sun, Xiangming Hu, Zhiqiang Nie, Haojian Dong, Guanghui Dong*, Yanqiu Ou*. Association of air quality improvement and frailty progression: A national study across China. Toxics, 2024, 12(7): 464.（大通讯作者，IF=4.6）
6. Yougen Yuan, Xiangming Hu, Junguo Jin, Jieliang Liu, Lujing Jiang, Guang Li, Yingling Zhou, Yanqiu Ou*, Haojian Dong*. Transition of visceral adiposity index and risk of cardiovascular disease in middle-aged and older Chinese adults. Archives of Gerontology and Geriatrics, 2024, 121: 105356.（共同通讯作者，IF=3.5）
7. Min Qiu, Jing Chen, Mingqin Liu, Yan Shi, Zhiqiang Nie, Guanghui Dong, Xiaohong Li, Jimei Chen, Yanqiu Ou*, Jian Zhuang*. Reprogramming of DNA methylation patterns mediates perfluorooctane sulfonate-induced fetal cardiac dysplasia. Science of the Total Environment, 2024, 919: 170905.（共同通讯作者，IF=9.8）
8. Xiangming Hu, Le-Bing Wang, Bin Jalaludin, Luke D. Knibbs, Steve Hung Lam Yim, Xiang Qian Lao, Lidia Morawska, Zhiqiang Nie, Yingling Zhou, Li-Wen Hu, Wen-Zhong Huang, Yanqiu Ou*, Guanghui Dong*, Haojian Dong*. Outdoor artificial light at night and incident cardiovascular disease in adults: A national cohort study across China. Science of the Total Environment, 2024, 918: 170685.（共同通讯作者，IF=9.8）
9. Haojian Dong, Peng Ran, Danqing Liao, Xiaobo Chen, Guo Chen, Yanqiu Ou*, Zhihao Li*. Long-term exposure to air pollutants and new-onset migraine: A large prospective cohort study. Ecotoxicology and Environmental Safety, 2024, 273: 116163.（共同通讯作者，IF=6.2）
10. Xiangming Hu, Yan Lin, Allison A. Appleton, Weimian Wang, Bingyan Yu, Langping Zhou, Guang Li, Yingling Zhou, Yanqiu Ou*, Haojian Dong*. Remnant cholesterol, iron status and diabetes mellitus: A dose-response relationship and mediation analysis. Diabetology & Metabolic Syndrome, 2024, 16(1): 65.（共同通讯作者，IF=94.4）
11. Xiangming Hu, Luke D. Knibbs, Yingling Zhou, Yanqiu Ou*, Guanghui Dong*, Haojian Dong*. The role of lifestyle in the association between long-term ambient air pollution exposure and cardiovascular disease: A national cohort study in China. BMC Medicine, 2024, 22(1): 93.（共同通讯作者，IF=9.3）
12. Rui Wang#, Xiangming Hu#, Yanqiu Ou#, Guoqiang Chen, Le-Bing Wang, Zhengmin Qian, Michael G. Vaughn, Maya Tabet, Li-Wen Hu, Guanghui Dong*, Haojian Dong*. Association between outdoor light at night and hypertension and high-normal blood pressure: A nationwide cross-sectional study among Chinese adults. The Journal of Clinical Hypertension, 2024, 26(2): 134–144.（共同第一作者，IF=2.8）
13. Xiangming Hu#, Zhiqiang Nie#, Yanqiu Ou#, Lizi Lin, Zhengmin Qian, Michael G. Vaughn, Stephen E. McMillin, Yingling Zhou, Yongjian Wu*, Guanghui Dong*, Haojian Dong*. Long-term exposure to ambient air pollution, circadian syndrome and cardiovascular disease: A nationwide study in China. Science of the Total Environment, 2023, 868: 161696.（共同第一作者，IF=9.8）
14. YuLing Luan, Yanqiu Ou*, Xiaoqing Liu, Shao Lin, Ying Guo*. Triclosan in paired-maternal and cord blood, and their relationships with congenital heart disease of baby.
Science of the Total Environment, 2023, 857(Pt 1): 159205. （共同通讯作者，IF=9.8）
15. Zunmin Wan#, Xiaohong Li#, Jinghua Sun, Xiaohua Li, Zhongzhen Liu, Haojian Dong, Qing Zhou, Hailong Qiu, Jinjin Xu, Tingyu Yang, Wen-Jing Wang*, Yanqiu Ou*. Peripheral blood transcripts predict preoperative obstructive total anomalous pulmonary venous connection. Frontiers in Cardiovascular Medicine, 2022, 9: 892000.（大通讯作者, IF=3.6）
16. Yanqiu Ou, Michael S. Bloom, Jinzhuang Mai, Melissa Francois, Wei Pan, Xiaohua Xiao, Ximeng Wang, Zhiqiang Nie, Yanji Qu, Xiangmin Gao, Yong Wu, Xiaoqing Liu, Jian Zhuang, Jimei Chen*. Prenatal detection of congenital heart diseases using echocardiography: 12-year results of an improving program with 9782 cases. Frontiers in Public Health, 2022, 10: 886262.（第一作者，IF=6.46）
17. Xiangming Hu#, Zhiqiang Nie#, Yanqiu Ou#, Zhengmin Qian, Stephen Edward McMillin, Hannah E. Aaron, Yingling Zhou, Guanghui Dong, Haojian Dong. Air quality improvement and cognitive function benefit: Insight from clean air action in China. Environmental Research, 2022, 214: 114200.（共同第一作者，IF=8.3）
18. Yanqiu Ou#, Xiaowen Zeng#, Shao Lin*, Michael S. Bloom, Fengzhen Han, Xiaohua Xiao, Hui Wang, Rosemary Matala, Xiaohong Li, Yanji Qu, Zhiqiang Nie, Guanghui Dong*, Xiaoqing Liu*. Gestational exposure to perfluoroalkyl substances and congenital heart defects: A nested case-control pilot study. Environment International, 2021, 154: 106567. （第一作者，IF=13.35）
19. Yanqiu Ou#, Michael S. Bloom#, Zhiqiang Nie#, Fengzhen Han, Jinzhuang Mai, Jimei Chen, Shao Lin, Xiaoqing Liu*, Jian Zhuang*. Associations between toxic and essential trace elements in maternal blood and fetal congenital heart defects. Environment International, 2017, 106: 127–134. （第一作者，IF=7.3）
20. Yanqiu Ou, Jinzhuang Mai, Jian Zhuang*, Xiaoqing Liu, Yong Wu, Xiangmin Gao, Zhiqiang Nie, Yanji Qu, Jimei Chen, Christine Kielb, Ursula Lauper, Shao Lin. Risk factors of different congenital heart defects in Guangdong, China. Pediatric Research, 2016, 79(4): 549–558.（第一作者，IF=2.3）
代表性课题
1. PFOS通过PGC1-a介导线粒体代谢重编程抑制心肌细胞分化和心脏发育的机制研究（82373529），国家自然科学基金面上项目，49万，2024.1-2027.12，立项，主持
2. 基于人群队列的围孕期铅与全氟辛烷磺酸复合暴露对子代先天性心脏病发生的作用及机制研究（81903287），国家自然科学基金青年项目，20万，2020.1-2022.12，已结题，主持
3. 全氟辛烷磺酸抑制LncRNA CARMEN/Gata4通路促进心脏间隔缺损发生的机理研究（2023A1515010801）,广东省自然科学基金，10万，2023-01至2025-12，结题中，主持
4. 广东省多种典型环境污染物联合暴露对先天性心脏病发生的关键作用及机制研究（No.2021A1515011445），广东省自然科学基金，10万，2021-01至2023-12，已结题，主持
5. 基于目标区域捕获测序的完全性肺静脉异位引流合并肺静脉狭窄的基因变异筛查与功能鉴定，省自然科学基金，10万，已结题，主持
6. 先天性心脏病和唇腭裂三级综合防控技术的应用示范和评价研究，国家重点研发计划，2297万，2018.7-2021.12，已结题，排名9/90，项目骨干
学术任职
1. 第七届中国高血压联盟青委 广东区主任委员
2. 第七届中国高血压联盟 常务理事
3. 粤港澳大湾区高血压联盟 常务理事
4. 广东省女医师协会高血压分会 副主委
执教课程（课程及教材建设）
转化医学
荣誉奖励
1. 广东省科技进步一等奖，广东省科学技术厅，2018
2. 宋庆龄儿科医学奖，宋庆龄基金会，2019
