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个人简介
2002.09--2007.07 中国医科大学临床医学专业本科
2007.09--2010.07 中国医科大学眼科学专业硕士研究生
2013.09--2016.07 中国医科大学流行病与卫生统计学专业博士研究生
2010.07--2014.11 中国医科大学附属第一医院眼科助教,医师
2014.12--2019.11 中国医科大学附属第一医院眼科副研究员,副主任医师
2017.03--2018.04 新加坡眼科研究所流行病学博士后
2019.09--2022.04 中国医科大学免疫学博士后
2019.12--2022.04 中国医科大学附属第一医院眼科教授,研究员,副主任医师
2022.05--至今 广东省人民医院眼科研究员、副主任医师
研究方向
眼病流行病学;人工智能;眼与全身病
代表性论著
1.Liu L, Tham YC, Cheng CY. Intravitreal aflibercept for proliferative diabetic retinopathy. Lancet. 2017. 390(10108): 2140-2141. (IF=202.73,中科院1区)
2.Liu L, Jiao J, Yang X, Zhang J, Yu H, Li C, Pan L, Ma B, Sun H, Zhang J, Li Y. Global, Regional, and National Burdens of Blindness and Vision Loss in Children and Adolescents from 1990 to 2019: A Trend Analysis. Ophthalmology. 2023:S0161-6420(23)00067-2. (IF=14.28,中科院1区)
3.Liu L, Li C, Yu H, Yang X. A critical review on air pollutant exposure and age-related macular degeneration. Sci Total Environ. 2022;840:156717. (IF=10.75,中科院1区)
4.Liu L, Tham YC. Re: Keel et al.: The prevalence of diabetic retinopathy in Australian adults with self-reported diabetes: The National Eye Health Survey. Ophthalmology. 2018;125(2):e13-e14. (IF=14.28,中科院1区)
5.Liu L, Quang ND, Banu R, et al. Hypertension, blood pressure control and diabetic retinopathy in a large population-based study. PLoS One. 2020;15(3):e0229665. (IF=3.75,中科院3区)
6.Liu L, Majithia S, Tham YC. Physical Activity and Age-related Macular Degeneration: A Systematic Literature Review and Meta-analysis. Am J Ophthalmol. 2018;185:123. (IF=5.49,中科院1区)
7.Liu L, Guan P, Cheng C. Paying more attention on keeping eye health in dust-haze weather in China. Environ Pollut. 2017. pii: S0269-7491(17)30981-8. (IF=9.99,中科院2区)
8.Liu L. Additional Comments on "Ten SNPs of PAX6, Lumican, and MYOC Genes are not associated with High Myopia in Han Chinese". Ophthalmic Genet. 2016;37(1):119-20. (IF=1.80,中科院4区)
9.Liu L, Yue S, Wu J, Zhang J, Lian J, Teng W, Huang D, Chen L. Prevalence and risk factors of retinopathy in patients with or without metabolic syndrome: a population-based study in Shenyang. BMJ Open. 2015;5(12):e008855. (IF=3.0,中科院3区)
10.Liu L, Wu J, Yue S, Geng J, Lian J, Teng W, Huang D, Chen L. Incidence Density and Risk Factors of Diabetic Retinopathy Within Type 2 Diabetes: A Five-Year Cohort Study in China (Report 1). Int J Environ Res Public Health. 2015;12(7):7899-909. (IF=4.61,中科院3区)
11.Liu L, Yue S, Wu J, Zhang J, Lian J, Huang D, Teng W, Chen L. The Prevalence and Distribution of Vitreoretinal Interface Abnormalities among Urban Community Population in China. J Ophthalmol. 2015;2015:742686. (IF=8.25,中科院1区)
12.Liu L, Zhou C, Du H, Zhang K, Huang D, Wu J; Anshan Worker Health Survey Group. The prevalences of impaired fasting glucose and diabetes mellitus in working age men of North China: Anshan Worker Health Survey. Sci Rep. 2014;4:4835. (IF=5.0,中科院2区)
13.Liu L, Chen L. Awareness of diabetic retinopathy is the key step for early prevention, diagnosis and treatment of this disease in China. Patient Educ Couns. 2014;94(2):284-5. (IF=3.5,中科院2区)
14.Liu L, Zhang D, Jiao JH, Wang Y, Wu JY, Huang DS. Association between the TP53BP1 rs2602141 A/C polymorphism and cancer risk: a systematic review and meta-analysis. Asian Pac J Cancer Prev. 2014;15(6):2917-22. (IF=2.51,暂未被收录)
15.Liu L, Jiao J, Wang Y, Wu J, Huang D, Teng W, Chen L. TGF-beta1 gene polymorphism in association with diabetic retinopathy susceptibility: a systematic review and meta-analysis. PLoS One. 2014;9(4):e94160. (IF=3.75,中科院3区)
16.Liu L, Jiao J, Wang Y, Zhang D, Wu J, Huang D. Lack of association of the TP53BP1 Glu353Asp polymorphism with risk of cancer: a systematic review and meta-analysis. PLoS One. 2014;9(3):e90931. (IF=3.75,中科院3区)
17.Tham YC#, Liu L#, Rim TH, et al. Association of Cataract Surgery With Risk of Diabetic Retinopathy Among Asian Participants in the Singapore Epidemiology of Eye Diseases Study. JAMA Netw Open. 2020;3(6):e208035. (IF=13.80,中科院1区)
18.Shi H#, Liu L#, Liu LM, Geng J, Chen L. Inhibition of tumor growth by β-elemene through downregulation of the expression of uPA, uPAR, MMP-2, and MMP-9 in a murine intraocular melanoma model. Melanoma Res. 2015;25(1):15-21. (IF=3.60,中科院4区)
19.Liu NN#, Liu L#, Li J, Sun YZ. Prevalence of and risk factors for dry eye symptom in mainland china: a systematic review and meta-analysis. J Ophthalmol. 2014;2014:748654. (IF=1.97,中科院4区)
20.Li C, Liang A, Kuang Y, Liu S, Yang X, Liu L, Hu Y, Yu H. Global burden of diseases attributed to mental and substance use disorders in reproductive-age women: an ecological analysis for the Global Burden of Disease Study 2021. Mol Psychiatry. 2025 Sep 8. (IF=10.1,中科院1区)
21.He X, Li C, Hua G, Wang Y, Zhang L, Cheng C, Jiao J, Yu H, Yang X, Liu L. Cross-national differences in the association between estimated cardiorespiratory fitness and depressive symptoms among older adults: findings from three nationwide cohort studies. BMC Med. 2025 Jul 1;23(1):363. (IF=11.80,中科院1区)
22.Zhang Z, Cai Z, Li C, Liu S, Li S, Liu L, Zhang L. Spatiotemporal trend of sensory impairments in China and its provinces from 2011 to 2018: insights from CHARLS. BMC Public Health. 2025 Nov 3;25(1):3752. (IF=3.60,中科院2区)
23.He X, Li C, Wang Y, Du Z, Jiang J, Zhang W, Peng J, Peng Z, Huang T, Li H, Kuang Y, Yu H, Liu L, Yang X. Association of Age-Related Eye Diseases with Comorbidity of Coronary Heart Disease and Depression in a Population-Based Cohort Study. Psychol Res Behav Manag. 2025 Sep 9;18:1931-1942. (IF=3.20,中科院3区)
24.Li C, Zhang L, Zhang J, Jiao J, Hua G, Wang Y, He X, Cheng C, Yu H, Yang X, Liu L. Global, regional and national burden due to retinoblastoma in children aged younger than 10 years from 1990 to 2021. BMC Med. 2024;22(1):604. (IF=11.80,中科院1区)
25.Li C, Hua G, Liu S, Yu H, Yang X, Liu L. Global, regional, and national burden of blindness and vision loss attributable to high fasting plasma glucose from 1990 to 2019, and forecasts to 2030: A systematic analysis for the Global Burden of Disease Study 2019. Diabetes Metab Res Rev. 2024 ;40(4):e3802. (IF=8.12,中科院2区)
26.Li C, Jing Z, Shen J, Liu S, Liu L, Yang X, Yu H. Global burden of vision loss attributable to household air pollution from 1990 to 2019: A trend analysis and 10-year prediction. Chin Med J (Engl). 2024 May 20;137(10):1231-1233. (IF=7.50,中科院3区)
27.Li C, Jiao J, Hua G, Yundendorj G, Liu S, Yu H, Zhang L, Yang X, Liu L. Global burden of all cause-specific injuries among children and adolescents from 1990 to 2019: a prospective cohort study. Int J Surg. 2024;110(4):2092-2103. (IF=15.30,中科院2区)
28.Li C, Fu Y, Liu S, Yu H, Yang X, Zhang M, Liu L. The global incidence and disability of eye injury: an analysis from the Global Burden of Disease Study 2019. EClinicalMedicine. 2023;62:102134. (IF=15.10,中科院1区)
29.Li C, Yu H, Zhu Z, Shang X, Huang Y, Sabanayagam C, Yang X, Liu L. Association of blood pressure with incident diabetic microvascular complications among diabetic patients: Longitudinal findings from the UK Biobank. J Glob Health. 2023 Mar 24;13:04027. (IF=7.66,中科院3区)
30.Li J, Li C, Huang Y, Guan P, Huang D, Yu H, Yang X, Liu L. Mendelian randomization analyses in ocular disease: a powerful approach to causal inference with human genetic data. J Transl Med. 2022;20(1):621. (IF=8.45,中科院2区)
31.刘磊,副主编,智能眼科概论,湖北科学技术出版社,2019年,ISBN:978-7-5706-0716-7。
32.刘磊,译者,OCT血管造影,北京科学技术出版社,2018年,ISBN:978-7-5304-9798-2R﹒2500。
33.刘磊,编委,医学数据处理与SPSS实用技术,辽宁教育出版社,2018年,ISBN:978-7-5549-2203-3。
34.刘磊,编委,眼底病人工智能研究,湖北科学技术出版社,2022年,ISBN:978-7-5706-1975-7。
代表性课题
1. 国家自然科学基金委员会,面上项目,儿童青少年屈光不正时空演变的环境驱动机制及智能防控体系研究,2026.01-2029.12,49万元,在研,主持;
2. 国家人力资源和社会保障部,眼底彩照与大规模生成式语言模型驱动心血管疾病动态预警系统开发与验证,2024.01-2025.12,50万元,结题中,主持;
3. 广东省人民医院,多中心眼病流行病学调查,2022.05-2027.05,200万元,在研,主持;
4. 国家自然科学基金委员会,基于BP人工神经网络的城市社区2型糖尿病视网膜病变预警模型研究,2014.01-2016.12,结题,主持;
5. 辽宁省委组织部,眼病分子流行病学研究,2019.01-2021.12,50万元,结题,主持;
6. 中国博士后科学基金会(特别资助),肠道菌群与糖尿病视网膜病变的关联性研究,2019.06-2021.05,18万元,结题,主持;
7. 中国博士后科学基金会,肠道菌群与2型糖尿病视网膜病变发生的机制研究,2019.11-2021.10,8万元,结题,主持;
8. 辽宁省教育厅,基于支持向量机的城市社区年龄相关性黄斑病变的预警模型研究,2017.01-2019.12,5万元,结题,主持;
9. 沈阳市科学技术局,基于大数据多组学的糖尿病视网膜病变相关遗传变异的初步探索和解析研究,2019.01-2021.12,10万元,结题,主持;
10. 2018年度“白求恩﹒朗沐中青年眼科科研基金”, 环境因素与VEGF基因多态性及其交互作用对康柏西普治疗糖尿病性黄斑水肿的影响,2019.01-2021.12,5万元,结题,主持;
11. 新加坡国家科技局,Agency for Science, Technology and Research,A*STAR,2020-2023,500SGD,结题,参与。
学术任职
1. 亚洲眼病流行病学协会会员;
2. 中华医学会数字医学分会青年委员会委员;
3. 中国医师协会眼科分会青年委员会委员;
4. 全国智能眼科学组常委;
5. 广东省医院协会眼病防治管理专委会副主任委员;
6. 辽宁省医学会眼科学分会青年委员会副主任委员;
7. 辽宁省医学会医学科普分会委员。
荣誉奖励
1. 刘磊,“兴辽英才计划”青年拔尖人才,辽宁省委组织部,2018年,证书编号:XLYC1807082。
2. 刘磊,辽宁省百千万人才“千”层次,辽宁省人力资源和社会保障厅,2018年,证书编号:LNBQW 2018 Q 0189。
3. 刘磊,沈阳市高层拔尖人才,沈阳市人力资源和社会保障局,2017年。
4. 刘磊,沈阳市中青年科技创新人才,沈阳市科技局,2019年,项目编号:RC190146。
5. 刘磊,基于BP人工神经网络的城市社区2型糖尿病视网膜病变预警模型,辽宁医学科技二等奖,2018年,证书编号2018-2-06-01。
6. 刘磊,Incidence Density and Risk Factors of Diabetic Retinopathy Within Type 2 Diabetes: A Five-Year Cohort Study in China(Report 1),辽宁省自然科学学术成果三等奖;2017年;证书编号:173203700833366。