个人简介

2007.09-2010.07  中山大学耳鼻咽喉科博士

2004.09-2007.07 江西省人民医院耳鼻咽喉科主治医师

2010.09-2012.11 江西省人民医院耳鼻咽喉科副主任医师

2012.12-2015.02 南方医科大学珠江医院耳鼻咽喉科博士后

2015.02-2017.10 南方医科大学珠江医院耳鼻咽喉科副主任医师

2018.01-至今 广东省人民医院耳鼻咽喉科主任医师

研究方向

鼻咽癌发病机制及靶向治疗研究；难治性鼻窦炎治疗与机制研究；纳米材料研发与应用；

代表性论著

[1]Liu HQ^#, Wu XD^#, Fang XW^#, An YS, Xia M, Luo XH, Li JZ, Wang GH*, Liu T*. Tumor-Targeted Magnetic Micelles for Magnetic Resonance Imaging, Drug Delivery, and Overcoming Multidrug Resistance. ACS Omega, 2024,9(50):49566-49579. (中科院小类3区，影响因子4.30)  

[2]Wenbo Wang^#, Shihao Zhou^#, Zhaoyi Cheng, Dong Ma^*, Tao Liu^*. A glutathione-sensitive cationic polymer delivery of CRISPR-Cas9 RNA plasmid for targeting nasopharyngeal carcinoma gene therapy. Colloids Surf B Biointerfaces,2023,223:113146. (中科院小类1区，影响因子5.40)     

[3]Lingling Xu^#, Xidong Wu^#, Huiqin Liu, Guangyuan Dong, Jiandong Zhan, Guanxue Li, Guanhai Wang^*, Tao Liu^*. Effects of combination docetaxel with NO treatment to enhance the anti-nasopharyngeal carcinoma efficiency in vitro and in vivo. EUR J PHARM SCI,2022,178:106281.中科院小类2区，影响因子4.60)  

[4]Lingling Xu^#,Chuan Zhou^#,Fan Wang^#,Huiqin Liu,Guangyuan Dong,Siyi Zhang^*,Tao Liu^*. Functional drug carriers formed by RGD-modified β-CD-HPG for the delivery of docetaxel for targeted inhibition of nasopharyngeal carcinoma cells. RSC Adv,2022,12(28):18004-18011. (中科院小类3区，影响因子3.90)   

[5]Guangyuan Dong^#, Yunsong An^#, Peikai Yan, Jiahui Wu, Chao Li^*, Tao Liu^*. A zeta potential-based homogeneous assay for amplifed detection of telomerase in cancer cells. Sensor Actuat B-Chem,2022,350,130881. (中科院小类1区，影响因子8.40)      

[6]Chao Li, Fei Wang, Tao Liu^*, Yucai Yang^*. A highly sensitive, dual-readout assay based on self-assembly of two functional nanoparticles for homogeneous detection of protein biomarkers[J]. Sensor Actuat B-Chem,2021,348,130710. (中科院小类1区，影响因子9.22)  

[7]Jiayu Huang^#, Jian Meng^#, Shaohua Chen^#, Siyi Zhang, Tao Liu^*, Chao Li^*, Feng Wang^*. A soft metal-polyphenol capsule-based ultrasensitive immunoassay for electrochemical detection of Epstein-Barr (EB) virus infection[J]. Biosens Bioelectron,2020,164:112310.(中科院小类1区，影响因子10.618)  

[8]Rui Li^#, Shuwei Chen^#, Jiandong Zhan^#, Xinghua Li^#, Wenlin Liu, Xiaoli Sheng, Zhongming Lu, Rong Zhong, Liangsi Chen, Xiaoning Luo, Yameng Hu, Ying Ouyang, Tao Liu^*, Quan Zhang^*, Siyi Zhang^*. Long noncoding RNAFOXD2-AS1 enhances chemotherapeutic resistance of laryngeal squamous cellcarcinoma via STAT3 activation[J]. Cell Death Dis,2020,11(1):41.(中科院小类2区，影响因子8.469)   

[9]Xiaoli Sheng, Wenlin Liu, Zhongming Lu, Mimi Xu, Rui Li, Rong Zhong, Yunxian Li, Tao Liu*, Siyi Zhang*. HTR7 promotes laryngeal cancer growth through PI3K/AKT pathway activation. Ann Transl Med,2021;9(10):840. (中科院小类4区，影响因子3.932)   

[10]Li Li^#, Tao Liu^#, Jia-Xin Liao, Zhe-Yi Zhang, Dai-Bo Song, Guan-Hai Wang*. Dual-responsive TPGS crosslinked nanocarriers to overcome multidrug resistance. J Mater Chem B,2020,8(36):8383-8394.(中科院小类2区，影响因子6.216)  

[11]Tao Liu^#*, Xidong Wu, Shaohua Chen, Peina Wu, Hong Han, Hongbin Zhang, Junzheng Li, Guanxue Li, Siyi Zhang*. A cationic polymeric prodrug with chemotherapeutic self-sensibilization co-delivering MMP-9 shRNA plasmid for a combined therapy to nasopharyngeal carcinoma. Drug Delivery, 2019,26(1):1280-1291.(中科院小类2区，影响因子4.902)   

[12]Tao Liu^#*, Jingzhen Li, Xidong Wu, Siyi Zhang, Zhongming Lu, Guanxue Li, Junzheng Li, Shaohua Chen*. Transferrin-targeting redox hyperbranched poly(amido amine)-functionalized graphene oxide for sensitized chemotherapy combined with gene therapy to nasopharyngeal carcinoma. Drug Delivery, 2019, 26(1):744-755.(中科院小类2区，影响因子4.902)    

[13]Tao Liu^#*, Shaohua Chen, Siyi Zhang, Xidong Wu, Peina Wu, Beiping Miao, Xiang Cai. Transferrin-functionalized chitosan-graft-poly(L-lysine) dendrons as a high-efficiency gene delivery carrier for nasopharyngeal carcinoma therapy[J]. J MATER CHEM B, 2018,6:4314-4325. (中科院小类2区，影响因子5.047)  

[14]Jing Chen^#, Hailiang Li^#, Bobo Li, Wei Li, Dong Ma, Yonghe Li*, Tao Liu*. Serum- and glucocorticoid-inducible kinase 3 is a potential oncogene in nasopharyngeal carcinoma[J]. BRAZ J OTORHINOLAR, 2019,85(6):705-715.(中科院小类4区，影响因子1.405)  

[15]Tao Liu^#*, Xidong Wu, Yigang Wang, Xiongjun Hou, Gang Jiang, Ting Wu, Huifen Xie, Minqiang Xie*. CD-PLLD co-delivering docetaxeland MMP9 siRNA plasmid for nasopharyngeal carcinoma therapy in vivo[J]. MOL MED REP,2017,16(2):1383-1388. (中科院小类4区，影响因子1.692)    

[16]Tao Liu^#*,Xinyu Zhang,Bo Ke,Yigang Wang,Xidong Wu,Gang Jiang,Ting Wu,Guohui Nie*. F-127-PEI co-delivering docetaxel and TFPI-2 plasmid for nasopharyngeal cancer therapy[J]. Mater Sci Eng C Mater Biol Appl,2016,61:269-277. (中科院小类2区，影响因子4.164)   

[17]Shansong Mu,Yuanyuan Liang,Shuaijun Chen,Liming Zhang*, Tao Liu*. MWNTs-hybrided supramolecular hydrogel for hydrophobic camptothecin delivery[J]. Mater Sci Eng C Mater Biol Appl,2015,50:294-299. (中科院小类2区，影响因子3.420)  

[18]Ting Wu,Bin Zhang,Yuanyuan Liang,Tao Liu*,Jinyan Bu, Lixing Lin, Zhimin Wu, Hongxi Liu, Shuiping Wen, Shaozao Tan, Xiang Cai*. Heparin-modified graphene oxide loading anti-cancer drug and growth factor with heat stability, long-term release property and lower cytotoxicity[J]. RSC Advances,2015,5: 84334-84342.(中科院小类3区，影响因子2.936)  

[19]Tao Liu, Wei Xue, Bo Ke, Minqiang Xie*, Dong Ma*. Star-shaped cyclodextrin-poly(l-lysine) derivative co-delivering docetaxel and MMP-9 siRNA plasmid in cancer therapy[J]. Biomaterials, 2014,35(12):3865-3872. (中科院小类1区，影响因子8.312)

[20]Hui-Qin Liu, Xi-Dong Wu, Xue-Wen Fang, Yun-Song An, Meng Xia, Xiao-Hua Luo, Jun-Zheng Li, Guan-Hai Wang, and Tao Liu. Tumor-Targeted Magnetic Micelles for Magnetic Resonance Imaging, Drug Delivery, and Overcoming Multidrug Resistance. ACS Omega 2024 9 (50), 49566-49579. DOI: 10.1021/acsomega.4c07132

[21]Yuhang Yu, Xidong Wu, Mengnan Ye, Jiaqi Zhang, Guochang Chen, Yaqi Peng, Luxuan Liu, Haiyong Ao, Guan-Hai Wang, Tao Liu, Therapeutic potential of metal-polyphenol network encapsulated S-nitroso glutathione for difficult-to-treat rhinosinusitis induced by methicillin-resistant Staphylococcus aureus, Journal of Drug Delivery Science and Technology, Volume 115, Part 2, 2026, 107765, ISSN 1773-2247, https://doi.org/10.1016/j.jddst.2025.107765.

[22]Luxuan Liu, Kai Lv, Xidong Wu, Guangyuan Dong, Yan Ge, Yiran Shao, Guowei Li, Dong Ma, and Tao Liu. Near-Infrared Light-Triggered NO/Photodynamic Synergistic Therapy with Antibacterial and Biofilm-Eliminated Effects for Difficult-to-Treat Rhinosinusitis. ACS Materials Letters 2024 6 (3), 780-792. DOI: 10.1021/acsmaterialslett.3c01421.

代表性课题

1.国家自然科学基金面上项目，于2019.12结题，50万元，主持，

2.广州市科技计划项目，2020.04.01至2023.03.31，20万元，结题，主持

3.广东省基础与应用基础研究基金项目，2019.10至2022.09，10万元，结题，主持

4.广东省医学领军人才和杰出青年医学人才配套科研项目，2019.10至2022.10，50万元，结题，主持

5.广东省人民医院科研基金人才引进类项目，2018.10至2021.12，50万元，主持，主持

学术任职

1.广东省医师协会耳鼻咽喉科医师分会鼻科专业组副组长；

2.广东省医学会耳鼻咽喉学分会青年委员会委员、咽喉学组成员及基础研究学组成员

3.中国抗癌协会康复会学术指导委员会委员。

4.国家自然科学基金医学科学7处项目评审专家。

执教课程（课程及教材建设）

1.实用耳鼻咽喉头颈外科疾病诊断与处理（2017年，科学技术文献出版社），副主编

荣誉奖励

1. 广州市科学技术奖励(科技进步类，三等奖)(2014-西医-3-03-R02).