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个人简介
1995.09--2000.07 山东中医药大学中西医结合专业 本科
2000.09--2003.07 山东中医药大学中医五官科(眼科)专业 硕士研究生
2003.09--2006.07 中山大学眼科学专业 博士研究生
2006.07--2009.09 中山大学中山眼科中心 医师、科研人员
2015.03--2016.03 美国约翰霍普金斯大学 访问学者
2009.10--至今 广东省人民医院眼科 研究员、副主任医师
研究方向
视网膜新生血管性眼病的发病机制;自身免疫性葡萄膜炎的基础与临床研究
代表性论著
(1) Wu X#, Liu J#, Zhu H, Wu G, Chen X, Guo T, Fang X*, Meng Q*. FoxO1, together with Notch1, promotes microglial activation to induce pathological changes in the retinal vasculature under hypoxia. Cell Mol Life Sci. 2025;83(1):12.
(2) Jin Y#, Liu J#, Zhang X, Zhang L, Cui Y, Luo X, Zhu H, Chen Z, Liu M, Wu X, Chen X, Liao S, Wu G, Fang X*, Meng Q*. Stage-dependent proteomic alterations in aqueous humor of diabetic retinopathy patients based on data-independent acquisition and parallel reaction monitoring. J Transl Med. 2025;23(1):476.
(3) Chen Z#, Liao S#, Chen G, Li C, Liu C, Liu J, Wu G, Lyu Z, Liu M, Wu X, Ma G*, Meng Q*. The Combination of Retinal Neurovascular Unit Changes With Carotid Artery Stenosis Enhances the Prediction of Ischemic Stroke. Transl Vis Sci Technol. 2025;14(3):14.
(4) Li X#, Wen X#, Shang X, Liu J, Zhang L, Cui Y, Luo X, Zhang G, Xie J, Huang T, Chen Z, Lyu Z, Wu X, Lan Y*, Meng Q*. Identification of diabetic retinopathy classification using machine learning algorithms on clinical data and optical coherence tomography angiography. Eye (Lond). 2024;38(14):2813-2821.
(5) Wu X#, Zhu H#, Liu J, Ouyang S, Lyu Z, Jin Y, Chen X, Meng Q*. Jagged1-Notch1 Signaling Pathway Induces M1 Microglia to Disrupt the Barrier Function of Retinal Microvascular Endothelial Cells. Curr Eye Res. 2024;49(10):1098-1106.
(6) Lyu Z#, Chen Y#, Zhu Z, Luo X, Cui Y, Xie J, Chen Z, Liu J, Wu X, Bulloch G, Meng Q*. Associations of concomitant retinopathy and depression with mortality in a nationally representative population. J Affect Disord. 2023; 336:15-24.
(7) Chen X#, Xie J, Cui Y, Zhang L, Yu H, Chen J, He M, Liu S, Huang T, Chen L, Fang D, Zhu Y, Zhang S*, Meng Q*. Cytoskeleton-associated protein 2 (CKAP2) is regulated by vascular endothelial growth factor and p53 in retinal capillary endothelial cells under high-glucose conditions. Mol Cell Endocrinol. 2021; 111378.
(8) Xie J#, Cui Y#, Chen X, Yu H, Chen J, Huang T, He M, Zhang L*, Meng Q*. VDAC1 regulates mitophagy in NLRP3 inflammasome activation in retinal capillary endothelial cells under high-glucose conditions. Exp Eye Res. 2021; 209:108640.
(9) Li X#, Xie J#, Zhang L, Cui Y, Zhang G, Chen X, Wang J, Zhang A, Huang T, Meng Q*. Identifying microvascular and neural parameters related to the severity of diabetic retinopathy using optical coherence tomography angiography. Invest Ophthalmol Vis Sci. 2020; 61(5):39.
(10) Cui Y#, Yang X#, Zhang G, Guo H, Zhang M, Zhang L, Zeng J, Liu Q, Zhang L*, Meng Q*. Intraocular Pressure in General and Diabetic Populations From Southern China: the Dongguan Eye Study. Invest Ophthalmol Vis Sci. 2019; 60(2):761-769.
(11) Meng Q#, Qin Y#, Deshpande M, Kashiwabuchi F, Rodrigues M, Lu Q, Ren H, Elisseeff JH, Semenza GL, Montaner SV*, Sodhi A*. Hypoxia-Inducible Factor-Dependent Expression of Angiopoietin-Like 4 by Conjunctival Epithelial Cells Promotes the Angiogenic Phenotype of Pterygia. Invest Ophthalmol Vis Sci. 2017; 58(11): 4514-4523.
(12) Meng Q#, Cui Y#, Zhang M, Zhang L, Zhang L, Zhang J, Kuang J, Liu Q, Zheng Y, Luo Z, Liu H, Zhu G, Cai J, Zhang G, Wen X, Guo H*. Design and baseline characteristics of a population-based study of eye disease in southern Chinese people: the Dongguan Eye Study. Clin Exp Ophthalmol. 2016; 44(3): 170-180.
(13) Meng Q, Zhang S*, Ling Y, Cui D, Jin Y. Long-term Anatomic and Visual Outcomes of Initially Closed Macular Holes. Am J Ophthalmol. 2011; 151(5): 896-900.
(14) Meng Q, Yang P*, Li B, Zhou H, Huang X, Zhu L, Ren Y, Kijlstra A. CD4+PD-1+ T cells act as regulatory cells during the induction of anterior chamber-associated immune deviation. Invest Ophthalmol Vis Sci. 2006; 47(10): 4444-4452.
代表性课题
1. 国家自然科学基金(82171072),2022.01-2025.12,57万元,结题,主持
2. 国家自然科学基金(81371031),2014.01-2017.12,70万元,结题,主持
3. 国家自然科学基金(30901653),2010.01-2012.12,20万元,结题,主持
4. 广东省自然科学基金(2021A1515010921),2021.01-2023.12,10万元,结题,主持
5. 广东省自然科学基金(2019A1515010697),2019.10-2022.09,10万元,结题,主持
6. 广东省自然科学基金(2017A030313609),2017.05.01-2020.05.01, 10万元,结题,主持
学术任职
1. 中国医师协会眼科医师分会葡萄膜炎与免疫专委会委员
2. 中国女医师协会眼科专委会视网膜病学组成员
3. 中国老年保健医学研究会眼科疾病防治分会委员
4. 广东省眼健康协会中老年眼保健专委会主任委员
5. 广东省医学会眼科学分会委员
6. 广东省医师协会眼科医师分会委员
执教课程(课程及教材建设)
1. 眼科学
荣誉奖励
1. 教育部科技进步二等奖,中华人民共和国教育部,2010
2. 广东省科技进步奖二等奖,广东省人民政府,2023